I am no part of the team of Manfred Jahn, but I am indeed one of the Calclassics forum goers, and a long time user of their planes, so I believe I can talk with a degree of adequacy here.
What you do wrong? I'd be ready to wager my family jewels, going by what you describe, that you treat a simulated plane rigged to be used as much as possible on like the real Constellation like it was a default plane.
Read the instructions. You
MUST
use ALL the attentions when managing the R-3350 in the Connies or you'll get four wrecks inside the nacelles that should house four growling powerful beasts. Starting off the engines you
MUST
manage the cowl flaps in the various stages of the take off, so not to overheat the cylinders heads; then you
MUST
keep the engines MAP pressure inside the limits of the current operational stage, so not to blow up the engines;
AND
, thing this a lot of people unused to constant speed props gets
ALWAYS wrong, you
MUST
keep the suggested number of rotations per minute for the stage of the flight you're in, so not to make the engines overheat and give up the ghost in flight (
flight, I may add, that won't last much longer after the engines have gone).
Not only that, everyone of those Connies has a Max operative Kias speed for the lowering and the use of flaps and gear. THAT TOO you
MUST
keep in mind while flying. If you don't, you will have to make due without the equipment you wrecked in flight.
Even more, ALL the Connies have an accurate mixture control and tanks management. Nothing to do nor alike the default FS controls. You
MUST
read the instructions to use those.
Keep in mind that here I hardly can suggest you how to manage the old lady correctly, what I wrote above is only a generic guide to make you understand what one should avoid to do to get bad results. To make the old lady dance, you should really read the instructions.
If you still need help, consider subscribing to the Calclassics forum and ask in that place. Jahn and all the others are always loitering there, it's their forum.