Skok,

Had a similar experience with my X45 long ago....it resulted from a break in the ground wire within the cable. I suspect it is the ground if indeed all functions have been lost.

The cable set-up on the X-45 is: Throttle plugs into the Joy and the Joy connects to the Computer. Looking at pics/descriptions of the X-52 I believe it's opposite, Joy to Throttle and Throttle to Computer. 

In my case, all of the functions on the Throttle became erratic, the Joy was fine. I brought up the Saitek calibration utility to watch for 'movement'. I then worked along the cable, bending and twisting, 'till I found the 'fault' area.

I split the cable sheath, unwrapped the foil shield and found the broken ground wire. I spliced the wire, taped things back up and have had no problems since.

Suspect areas of the cable where is has been bent, kinked or stretched, particularly near the strain reliefs.

Dave

If you want, you could simply replace the cable... the Saitek support forum is filled with people having cable trouble and asking for a replacement...

Basically, the cable you're looking for is a 6-pin, male to male Mini DIN (PS/2) cable, which should be available in electronics stores or on the internets... it's not a proprietary cable as they would have you think 

Cheers