Y'know, I was thinking of past incidents I'd heard of involving doors opening in flight, but I realize of course that those were aboard aircraft with out-swinging doors... the new design not only has the advantage of acting as a plug under pressure, but some even have an extra latching mechanism engaged by the force of the pressure, if I understand correctly... so that scenario is probably the least likely to be a problem.
Should a door be opened when cabin/ambient pressure is equal, the only danger would be in somebody falling out, as opposed to the usual hazrds of a rapid decompression of the cabin.
But regardless, I'm all in favor of airlines and the government adopting a "zero tolerance" policy towards disruptive passengers.
Like that brat who was kicking the back of my seat on a flight from Miami to New York one time... yes, he was aware he was annoying me; a glance back confirmed he was pleased with himself, the little monster...

the elderly woman escorting him pretended she didn't notice, so finally I had to turn around, lean way over the back of my seat to get right in his face, and growl: "Stop it. Now."
Oddly enough, it worked!!

The only snag of course with the drunks, etc. is dealing with those who are already intoxicated when they show up at the gate... unless they start making trouble right then and there, or are clearly out of it, they'll be let aboard... oh well. Best to have a drink and forget about it, I guess...