I got the Triple Head 2 Go... and i feel it surpasses multiple video cards in one aspect, it is not hardware-dependent...
the main benefit of the TH2Go is it's portability, being able to keep your 3 screens when you change your hardware, regardless of which or how many GPUs you have
the down side though, is that, when compared to a triple GPU setup, the very high resolution imposed by the TH2Go is very demanding on hardware, and will somewhat lag your system if you don't have the horsepower to back it up... but given that you DO have 3 GPUs, i don't think it would be your case
SLI for FSX doesn't yeald much gain on FPS, except for very high AA and resolution situations, which a triple monitor setup pretty much implies...
so, in my view, you have 2 options:
one, have your 3 cards working as one in SLI mode and hook up a triple head in the primary output... this i would recommend if you didn't have top notch cards, and had less than 3 of them while at it
or, which i think is more sensate in your case, just use one GPU per screen, and be happy
...i think you'll have to disable SLI for that.. but when your cards are GTX 280s, who cares, right?
Cheers