Yes, I believe plans to complete a second airframe are still in progress. Great news!!

Actually, if I remember correctly in my infinite wisdom of the Antonov Super Heavy line, the An-325, was simply a concept, designed to carry HOTOL. It was said to have 8 engines, 4 of them carried B-52 style. Anyway, get much bigger than the 225, and you are looking at unflyable.

There is no reason why an aircraft cannot be larger than the -225 and still be able to fly. If you fulfill 1 of 2 of the following conditions, anything will fly.
a) provide enough vertical thrust to counteract the effect of gravity.
b) provide a large and strong enough wing with sufficient airflow to produce enough lift to counteract the force of gravity.
Granted, we reach a point where fulfilling the above is impractical.

The only reason an aircraft larger than the an-225 would be improbable is that it would be so limited as to where it can and cannot land, that it would be almost impossible to find any practical application for an aircraft of its size.

Eh, larger plane in terms of WINGSPAN. Also it only flew 4 ft above the sea. 

Also, I reserve the right to sue the thread poster for using my name. See you in court on Monday. 

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Actually he used An 225. You are An-225

I thought it made 6 feet.

Trojan Rabbit, the second point you made is the most far-fetched thing I have ever heard. The market DOES want jumbos - the bigger (A380) the more people it can carry in one flight, and the faster the money rolls in. They don't want a crappy little Dreamliner taking only a few hundred people across nations at one time - more flights would then have to be made, meaning they will LOSE money (more flights = pilots with higher paychecks).

Also, the Antonov An-325, would not be a jumbo. It would be a CARGO carrier, and the market would love that, as it means they can carry more cargo in one flight.

In the end...your logic simply does not work.