I use the Saitek X52.   Worth every penny.   But then, I also fly Wings Over Vietnam and can't tell you helpful the numerous programmable buttons come in handy there.

I've used the Saitek X-45 for almost three years now and absolutely love it.  I've looked at the X-52, but I think it's a little too gimmicky for my tastes.

I love my X-45:) Response is impeckable. My friend however has the X-52 and says its better. Ive flown with the X-52 and really dont like it. Ya sure it looks better, but there are too many buttons that ide leave un progarmmed. for instance what does everyone have the knobs on the X-45 throttle programmed to? currently mine are nothing, because i see no need for them. so ya, X-45 all the way, unless you wanna go the sim pilot route and get one of those throttle and joysticks from an actual aircraft $$$ but its your choice. NOW CHOOSE SAITEK X-45