I'm still a FS98 fan.  It runs on anything.  I recently bought a copy of Abacus' Co-Pilot on eBAY.  It is supposed to automatically fly your plane from point-a to point-b, OR use your flightplan.  It includes a scrolling map for ease of navigation. 

It is complex to use, and compared with share-ware, such as EASYFLY by Warren software (1999), it pales.  The only problem with EasyFly, is that they have a trial version on Flightsim.com that is limited in scope.  If anyone has the full version, I sure would appreciate it.